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The proper function of the brain requires the concerted action of billions of interconnected brain cells called neurons. Most neurons are excitatory and their activation releases glutamate, which increases brain activity. However, some are inhibitory and their activation releases GABA, which decr...
Without movements, we are relegated to being trapped inside ourselves. Our understanding of the distributed brain circuits responsible for deciding what, how and why to perform movements has been limited by an inability to characterize how distributed networks of interlinked neurons orchestrate b...
The specialized chemosensory cells within the tongue and gut relay appetitive and aversive signals to the brain via peripheral ganglion neurons. Taste dysfunction is common in adults (17%) and even more prevalent in the aging population.
Visualizing the flow of information through the complex and intertwined networks of the brain is a long‐sought goal of neuroscience.
Determining how distinct memories are formed, linked, and retrieved, and the role of fear in these processes, is an essential part of understanding PTSD, a debilitating disorder characterized by the re-experiencing of a traumatic event in the form of persistent and intrusive memories.
Social interactions play a crucial role in the reproduction, survival, and physical and mental health of many vertebrate species including humans. Impairment in social behavior is a hallmark of several…
The central question in my proposal is whether our perception of time and space share the same circuit mechanisms during our daily life. Recent studies suggest that neurons in the…
Tremor is a prevalent and often debilitating disorder for many individuals; however, the cause of tremor remains poorly understood. We have previously identified alterations in the cerebellum, the brain region…
DNA from a single human cell is more than 6 feet long when stretched out end to end. Recent technological advances have revealed that the 6 feet long DNA sequence…
Neurodegenerative disorders arise as components of the nervous system deteriorate with age. The symptoms accompanying this deterioration become progressively worse, compromising an individual’s ability to function. The progressive and widespread…
Be a part of the impact. Stay up-to-date with BRF news, including new programs, upcoming events, and updates on our brain research journey.