In mammals, the control of movement relies on networks of neurons in many different brain regions. A major pathway linking different motor circuit is in the brainstem, linking ‘upstream’ neurons…
Alzheimer’s disease (AD) is an irreversible, progressive brain disorder. AD destroys neurons,causing memory loss, confusion and impaired judgment. It is characterized by the formation oftwo pathological features, plaques and tangles.…
Epilepsy is a brain disorder of abnormally increased brain excitability that leads to seizures. Aperson is considered to have epilepsy when he or she has two or more unprovoked seizures.Advances…
A hallmark feature of our brains is their enormous capacity for information storage and learning.In neuronal circuits, information is stored through long-term changes in the efficacy and gain ofsynaptic communication,…
Harsh, abusive maternal parenting in childhood is a robust risk factor for many mental disordersand health problems including cardiovascular disease, diabetes, and obesity. Studies of non-human mammals reveal that atypical…
Fragile X syndrome is the most common form of human mental retardation and the singlelargest known cause of autism. One prominent manifestation of the disease is an alteration insensory processing…
In mammals, the control of movement relies on networks of neurons in many different brain regions. A major pathway linking different motor circuit is in the brainstem, linking ‘upstream’ neurons…
More than 600,000 people in the U.S. have severely impaired motor function from disorders including amyotrophic lateral sclerosis, brainstem stroke, and spinal cord injury. The cost of caring for these…
Using the data collected from his 2009 Seed Grant, Dr. Jeremy Amiel Rosenkranz was able to turn this $40,000 grant into over $1.5 million in additional funding from…
Our lab is interested in understanding events that lead to chronic degenerative diseases that affect the brain. Currently we are studying a genetic disease that leads to cerebellar pathology called…
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