Neural stem and progenitor cells generate the massive diversity of neurons and glia that comprise the nervous system. Understanding the regulation of how neural progenitors divide and differentiate will provide…
The “trace amines” are normal chemicals found in the brain that have been associated with neurological disorders such as depression, schizophrenia, attention deficit hyperactivity disorder, and addiction. In the last…
Her investigations into neurorepair will support Dr. Ardelt’s clinical work with stroke patients and also have the potential to advance the treatment of other brain disorders. Suffering a…
Ravi Allada, M.D., Professor of Neurobiology at Northwestern University, is interested in the molecular mechanisms underlying circadian rhythms and their links to various clinical disorders, including insomnia, depression and even…
Dr. Awatramani proposes that there is a developmental basis for dopamine neuron diversity. In other words, during embryonic development, the dopamine progenitor pool is parceled in a manner meaningful to…
Dr. Opal is studying a genetic disease called Spinocerebellar Ataxia Type 1 that affects the cerebellar region of the brain. This is a relentless and uniformly fatal disease with no…
Dr. Lazarov’s investigation of neurogenesis in adult stem cells will lead to greater understanding of Alzheimer’s disease. When Dr. Orly Lazarov sought to understand certain cellular processes associated with the…
The results of this work will provide new insights into the molecular mechanisms of vesicle fission during CME. I expect that my research will significantly contribute to our knowledge of…
Dr. Wang proposes a new collaboration between chemists, biomedical and electrical engineers and neuroscientists to develop a MRI contrast method that directly assesses neural activity in real time. This new…
The majority of natural scents encountered in the environment are complex mixtures of dozens, or even hundreds, of different molecular constituents. Thus a key challenge for the olfactory system is…
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