Why do so many of us struggle with addiction or depression, or both? A BRF grant is helping Mitchell Roitman, Ph.D., look for answers. “Our work has implications for…
Dr. Prakriya will use his 2012 Seed Grant to illuminate the calcium signaling mechanisms regulating the development of neural stem cells. Specifically, the Prakriya lab will investigate the hypothesis that…
Humans are highly visual animals and loss of any visual function can severely impact quality of life. Visual problems are among the ten most prevalent causes of disability in America…
The human eye sends information to the brain at an estimated rate of approximately 10 megabits per second, roughly the speed of an ethernet connection. Processing such a large bandwidth…
Age-related macular degeneration (AMD) is the most common cause of visual impairment in Americans over the age of 60. Every year, 700,000 new cases of AMD are diagnosed and 10%…
Dopaminergic neurons located at the ventral midbrain control movement, mood and motivation. Dysfunction of dopaminergic neurons is implicated in Parkinson’s disease, drug addiction, depression and schizophrenia. Generating dopaminergic neurons from…
Humans and other advanced animals have an impressive capacity to learn and recognize the behavioral significance, or category membership, of a wide range of sensory stimuli. This ability, which is…
Existing drugs used to treat depression are mostly aimed at a set of chemicals in the brain (including serotonin), but they don’t work effectively in up to half of the…
Periventricular Heterotopia (PH) caused by mutations of the Filamin gene is a congenital brain developmental disease that affects both brain structures and functions. A mouse model of PH by inactivating…
The “trace amines” are normal chemicals found in the brain that have been associated with neurological disorders such as depression, schizophrenia, attention deficit hyperactivity disorder, and addiction. In the last…
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