2012-2013 Research Topics


In 2012, the Brain Research Foundation Seed Grant Program funded critical research in 10 areas of neuroscience. In addition to our annual seed grant program, the Foundation awarded two larger grants to distinguished investigators in 2012 and 2013 for our Scientific Innovations Award. Drs. Ben Barres, W. Martin Usrey, Jean M. Hébert and Brian Litt were chosen to receive $150,000 each to pursue exciting research in neuroscience. Click on each of the topics below to learn more about the studies and how they’ll contribute to the field of neuroscience.

Click here to find out about previous research topics.

Human Cognition
An Astrocytic Basis for Humanity
2012 Scientific Innovations Award
Ben Barres, M.D., Ph.D.
Department of Neurobiology
Stanford University

Cortical Function & Behavior
Optogenetics in the Behaving Primate: Using Light to Study Cortical Function
2012 Scientific Innovations Award
W. Martin Usrey, Ph.D.
Center for Neuroscience
University of California, Davis

Neuron Replacement: Improved Cognitive Function
How receptive is the adult neocortex to incorporating new projection neurons?
2013 Scientific Innovations Award
Jean M. Hébert, Ph.D.
Department of Neuroscience
Albert Einstein College of Medicine

Targeted Therapy with Nanodevices
Nanodevices to Treat Neurological Diseases
2013 Scientific Innovations Award
Brian Litt, M.D.
Department of Neurology
University of Pennsylvania

Depression
Novel HCN channel inhibitors for treatment of depression
2012 Seed Grant
Dane Chetkovich, M.D., Ph.D.
Department of Neurology
Northwestern University

Learning and Memory
Cortical circuit mechanisms for visual categorization and category learning
2012 Seed Grant
David Freedman, Ph.D.
Department of Neurobiology
The University of Chicago

Parkinson's Disease
Regulation of Dopaminergic Neuron Fate Specification by Neurogenin 2
2012 Seed Grant
Yong-Chao Ma, Ph.D.
Department of Pediatrics, Neurology and Physiology
Northwestern University/Children's Hospital Research Center

Age-related macular degeneration (AMD)
Characterization of infrared neural stimulation in the retina
2012 Seed Grant
Agnella Matic, Ph.D.
Department of Otolaryngology
Northwestern University

Visual Processing
Neural mechanisms of efficient coding in the primate visual cortex
2012 Seed Grant
Leslie Osborne, Ph.D.
Department of Neurobiology
The University of Chicago

Hormonal Effects on Neurons
Modulation of visual cortical processing by brain-generated estrogen
2012 Seed Grant
Raphael Pinaud, Ph.D.
Department of Neurobiology
Northwestern University

Neural Stem Cells
CRAC channel function and calcium dynamics in neural stem cells
2012 Seed Grant
Murali Prakriya, Ph.D.
Department of Molecular Pharmacology and Biological Chemistry
Northwestern University

Processing Emotion - Depression and Drug Addiction
Optogenetic induction of phasic pauses in dopamine signaling in awake, behaving rats
2012 Seed Grant
Mitchell Roitman, Ph.D.
Department of Psychology
University of Illinois Chicago

Galectins - How They Alter Brain Function
Galectin modulation of excitatory transmission and neuronal function
2012 Seed Grant
Geoffrey Swanson, Ph.D.
Department of Molecular Pharmacology and Biological Chemistry
Northwestern University

Schizophrenia
CB1 cannabinoid receptor activation during adolescence impairs maturation of prefrontal GABAergic circuits
2012 Seed Grant
Kuei Tseng, M.D., Ph.D.
Department of Cellular and Molecular Pharmacology
Rosalind Franklin University